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Retatrutide is an investigational peptide drug developed by Eli Lilly that acts as a triple agonist, simultaneously targeting three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

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Similarly, Eli Lilly is exploring the combination of their amylin analog, Eloralintide, with other GLP-1-based treatments like Retatrutide or Tirzepatide

Slifer, Z

Increased small intestinal permeability and RNA expression profiles of mucosa from terminal ileum in patients with diarrhoea-predominant irritable bowel syndrome